In the biomedical field, several nanotechnology-based approaches have influenced the development of therapeutic drugs and pharmaceutical formulations. In particular, the increasing burden to human health caused by serious diseases (e.g., various types of cancers, coronary artery disease (CAD), etc.) has required ongoing innovations in drug delivery and drug-eluting systems, many of which rely on nanotechnology.
The main applications of these new drug-delivery and targeting systems have been focused on imaging agents for cancer diagnosis and the development of new anticancer drugs and strategies. Nanocarrier-based delivery systems can be used to increase the safety and efficacy of active ingredients in medical, particularly when such ingredients are unstable, sparingly soluble, or cause off-target effects. Biocompatible inorganic material-based nanosystems provide a novel choice to effectively circumvent the intrinsic drawbacks of traditional organic materials in biomedical applications, especially in overcoming the multidrug resistance (MDR) of cancer cells due to their unique structural and compositional characteristics, for example, high stability, large surface area, tunable compositions, abundant physicochemical multi functionalities, and specific biological behaviors. In view of this, the main goal of this winter school is to examine inorganic nanoparticle-based carrier systems (gold nanoparticles, quantum dots, upconversion nanoparticles, etc.) for the delivery of therapeutic agents such as drugs, genes, and various biomolecules, with an emphasis on the structural and biological aspects.